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Non-hydroxylated collagen is unstable, and the normal processes of tissue repair cannot occur
The review also documented how GCL expression is transcriptionally upregulated by electrophiles through antioxidant response elements (ARE/EpRE) in the GCLC and GCLM promoters establishing the Nrf2/ARE pathway as the master regulator of GSH biosynthetic capacity under stress conditions
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doi: 10.1096/FJ.02-0633FJE 107 The interaction effect of MDSC and mTOR signaling pathway by iNOS and NO in asthma
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