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Sikiri et al., Burns 2003, 29, 323334
6.1 -Cell damage by ROS Pancreatic -cells exhibit a unique vulnerability to OS due to their inherently low expression of antioxidant enzymes (SOD, CAT, and GPx) and their high metabolic activity, which generates substantial ROS under hyperglycemic conditions ( cells have been proposed, among which are hyperglycemia, hyperlipidemia, hypoxia, and endoplasmic reticulum (ER)
It is also rich in vitamins A, C and E that help to increase its antioxidant properties
However, the high prevalence of VD deficiency in PD patients could also be the result of reduced outdoor activity owing to activity restriction, and the possibility that gastrointestinal dysfunction (a non-motor PD symptom) leads to lower VD2 levels in PD patients cannot be completely ruled out
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