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69 Changes in the enteroendocrine system in T2DM In T2DM patients, incretin hormone effectiveness is reduced, with esophagogastroduodenoscopy showing lower GLP-1R expression in gastric mucosa biopsies compared to non-T2DM patients, potentially impairing incretin axis function

Researchers note that intranasal delivery may especially increase the bioavailability of peptide therapeutics and present an appealing alternative to injection [14, 15, 16]

GLP-1 receptor agonists take center stage, tickling the brain's appetite regulation center in the hypothalamus and leaving it giggling with delight

Ahmet Murat What the trials actually show Adult trials: mild Wegovy hair loss around the low single-digit range compared with placebo