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That weight loss is largely from fat mass, including a disproportionately large reduction in visceral abdominal fat and improvements in waist circumference
This concern is particularly relevant for patients with stricturing CD, in whom up to 50% develop fibrostenotic complications within 10 years of diagnosis (74)
Sexual side effects should be taken seriously, and sometimes small adjustments (like dose changes, hormone testing, or support meds) can make a big difference
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