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Acetyl Tetrapeptide-3 Mechanism: This peptide strengthens the extracellular matrix around hair follicles, improving hair anchoring and reducing shedding

The observed alleviation of this inhibition (by NaBH 4 -reduced gliotoxin), in the presence of added GSH, supports the proposal that intracellular GSH depletion is a consequence of gliT disruption, when growth occurs in the presence of exogenous gliotoxin

Discontinuation rates from the phase 2 trial due to side effects were generally low, though the broader literature on GLP-1 receptor agonists notes that discontinuation rates across the class can reach 20-50% within the first year