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(PubMed) O'Gara EA, Hill DJ, Maslin DJ
A large trial reported in 1994 (pdf) that daily megadoses of the antioxidant beta-carotene increased the risk of lung cancer in male smokers by 18 percent and a 1996 trial was stopped early after researchers discovered that high-dose beta-carotene and retinol, another form of vitamin A, increased lung cancer risk by 28 percent in smokers and workers exposed to asbestos
Conversely, the pharmacological induction of GPx4 has been demonstrated to inhibit radiation-induced ferroptosis and to offer radioprotection in the murine model [67]
Given how quickly this status has changed since 2023, readers should treat ipamorelin's compounding legality as unsettled rather than fixed, and verify current status directly with the FDA or a licensed pharmacist before assuming a lawful compounding pathway exists
