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Renal fibrosis and glomerulosclerosis are two major pathological changes in CKD, with renal fibrosis, glomerulosclerosis, tubulointerstitial fibrosis, inflammatory cell infiltration and renal parenchymal loss collectively contributing to fibrosis progression

Bile-acid-activated receptors: targeting TGR5 and farnesoid-X-receptor in lipid and glucose disorders

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Free Radic Biol Med 27(910):951965 Branco V, Coppo L, Sol S, Lu J, Rodrigues CMP, Holmgren A, Carvalho C (2017) Impaired cross-talk between the thioredoxin and glutathione systems is related to ASK-1 mediated apoptosis in neuronal cells exposed to mercury