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Tirzepatide is a dual agonist, affecting both GLP-1 and GIP (glucose-dependent insulinotropic polypeptide) receptors
Study has proven that TGF- signaling in retinal endothelial cells is amplified in early DR, promoting collagen cross-linking and basement membrane rigidity ( 2.1.2 Pericyte apoptosis Pericyte apoptosis is universally recognized as the earliest functionally significant and morphologically identifiable lesion in diabetic retinopathy, occurring months to years before microaneurysms become visible clinically
They work by mimicking a naturally occurring hormone in the body to stimulate the secretion of insulin
It should not be considered a substitute for any prescribed medication
