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The X-IPA system provides quantitative insights into the effects of luminal perturbations on gut permeability at the whole-tissue level, thus bridging the gap between simplified in vitro assays and complex in vivo animal models
In cerebral microdialysis study in rats, significantly higher brain intracellular distribution of ketoprofen was reported after LAT1-utilizing derivative of ketoprofen compared to parent drug dosing (112)
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Schisandrin B prevents doxorubicin-induced cardiotoxicity via enhancing glutathione redox cycling
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