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FIGURE 1 In the original analysis, classification appeared to be supported by functional data such as substrate selectivity and inhibition characteristics (Mannervik et al., 1985)

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The results with semaglutide alone are encouraging and suggest a potential new treatment option for a group of patients who previously had very few. The Phase II trial followed about 700 adults with biopsy-confirmed MASH and moderate to advanced liver scarring, including participants who had already developed early cirrhosis