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The gastrointestinal tract, from the stomach to the colon is the principal target for GLP-2 action
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According to a 2021 review, "[Less than 10%] of the intact molecule reaches the plasma and tissues."35 With that in mind, you'll want to look for a brand that maximizes absorption through some mechanism like a liposomal delivery system
doi: 10.22074/cellj.2021.7222 25 EbrahimiFRostamiSNekoonamSRashidiZSobhaniAAmidiF
The enhanced helical structure increases receptor affinity by reducing the entropic cost of adopting the bioactive conformation, while the D-amino acid protects against DPP-IV cleavage that normally represents a major degradation pathway
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