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Interestingly, both in vitro and in vivo work in rodents demonstrated that GLP-1RAs can promote growth-related phenotypes by enhancing osteoblast proliferation and activity 9,10

The quantitative bias analysis suggested that moderate unmeasured confounding could potentially explain away an HR of 0.86 observed with SGLT2 inhibitors versus DPP4 inhibitors, whereas stronger unmeasured confounding is needed to explain away larger HRs observed in as-treated analyses (Supplementary Fig

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An active ingredient is what makes a drug work