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They mimic a naturally occurring hormone called glucagon-like peptide-1 (GLP-1), which helps regulate blood sugar levels and appetite
However, well-designed human clinical trials assessing the safety and effectiveness of this combination are still lacking, and the majority of the information currently available comes from animal and in vitro studies
It is reflected in mortality data showing that cardiovascular disease is a leading cause of death in SLE, particularly in patients who survive the first five years after diagnosis
2022;15:5848 Specian RD, Neutra MR
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