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We thank Andy Waters for providing the Pb ANKA parasite lines, Tobi Spiellman for providing the PfK13 knocksideways line, David Fidock for providing the Cam3.II lines, Leann Tilley for providing the PL2 and PL7 lines, and the Malaria Research and Reference Reagent Resource Centre (MR4) for providing the MRA lines

Oxoproline is a cyclic form of glutamate and is converted into glutamate via oxoprolinase (Figure 5)

Clinical trial data for FDA-approved GLP-1 receptor agonists demonstrates: Significant weight reduction: Meaningful mean body weight reduction in trial participants (see FDA-approved labeling for specific approved products) Cardiorenal protection: Reduced risk of major adverse cardiovascular events and kidney disease progression Improved lipid profiles: Decreased triglycerides and increased HDL cholesterol Blood pressure reduction: Modest but clinically significant decreases in systolic blood pressure Reduced inflammation: Decreased inflammatory markers associated with metabolic syndrome Note: Clinical outcomes cited above reflect published trial data for FDA-approved GLP-1 receptor agonists