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Similarly, the chemoenzymatic approach also led to the synthesis of a cathepsin C-selective inhibitor, a derivative of E-64c hydrazide 65 , with 26% total yield (Fig
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Reduced incretin effect in type 2 diabetes: cause or consequence of the diabetic state
Long-term safety data continues to accumulate, and a comprehensive 2024 review in Diabetes Care by Daniel Drucker concluded that the overall risk-benefit profile of GLP-1 medicines remains favorable for their approved indications
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