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Duntas LH, Papanastasiou L, Mantzou E, Koutras DA (1999) Incidence of sideropenia and effects of iron repletion treatment in women with subclinical hypothyroidism
Under hypoxic conditions, cells activate adaptive responses mediated by hypoxia-inducible factor-1 (HIF-1), which regulates genes involved in angiogenesis, cell survival, and glucose metabolism
After significant weight loss, patients commonly develop: Loose abdominal skin Stretch marks Lower abdominal overhang Muscle separation (diastasis recti) Persistent skin laxity No medication can tighten stretched abdominal skin or repair separated abdominal muscles
The most common side effects are gastrointestinal nausea, diarrhea, constipation which often improve over time
