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Interestingly, numerous in vivo studies have shown that mushroom polysaccharides are capable of protecting the antioxidant activities of enzymes such as superoxide dismutase (SOD), catalase (CAT), and glutathione peroxidase (GSH-Px), which are major components of the defense system against ROS within body ( Tremella fuciformis polysaccharides (TFPS) markedly improved the SOD and GSH-Px activities in serum, liver, and heart tissues in D-galactose-induced aging mice (46)