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Anyone with significant medical conditions, anyone pregnant or breastfeeding, and anyone on multiple medications needs a careful review first not because problems are expected, but because limited human data means we don't assume
Furthermore, vitamin B12 can't be stored over the long term by our bodies, so it has to be consumed regularly to maintain adequate levels
Starting at 250-300mcg regardless of body weight, then adjusting based on response, often works better than jumping to weight-based higher doses
Then, they do weekly injections for a month
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