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Individuals with certain health conditions, such as Lebers disease (a rare inherited eye disease), should avoid B12 supplements as it can worsen the condition

If you experience some discomfort after receiving a B12 injection at our office, rest assured that this is generally a normal and mild reaction

While it is known that B-vitamin supplementation effectively treats hyperhomocysteinemia, there is a need for well-designed, large trials to evaluate the effect of B-vitamin supplementation on long-term outcomes, such as age-related cognitive decline and the incidence of Alzheimers disease

[PMID: 36797299] PubMed record related to this compound for laboratory literature review