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Cell Metab 27(4):740756 Smith NK, Hackett TA, Galli A, Flynn CR (2019) GLP-1: Molecular mechanisms and outcomes of a complex signaling system

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Summary: IGF-1 promotes growth of all cells even unhealthy ones

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The intestinal-hepatic crosstalk constitutes a pivotal component of MASLD development, linking intestinal dysbiosis to hepatic inflammation and fibrosis [1]

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This heightened metabolic activity naturally produces more free radicals

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