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After a month, the dose is gradually increased to 0.5mg for the next month
Women aged 25-45 with BMIs between 25-28 kg/m were randomly assigned to one of two groups: [5] Supresa group: 176.5 mg of standardized saffron extract daily (split into two doses) Placebo group: Identical-looking capsules with no active ingredients A key point that differentiates this study from many weight loss trials is that participants were not placed on any caloric restrictions
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CHAC1 degrades GSH, reducing the GSH/GSSG ratio and impairing the activity of GPX4, an enzyme essential for detoxifying lipid peroxides
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