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And they stayed on protocol because the gradual starting dose made the journey tolerable

Cardiovascular outcomes with GLP-1 receptor agonists in patients with type 2 diabetes

In summary, amino acid metabolism precisely regulates the ferroptotic process through several distinct pathways, such as the Xc-/GSH/GPX4, FSP1/DHODH/CoQ, GCH1/BH4, NRF2/SLC7A11/GPX4, and AMPK (Figure 4)