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Patients experiencing persistent gastrointestinal side effects from Wegovysuch as severe nausea or vomitingshould be cautious about taking any oral medications and should contact their healthcare provider if symptoms prevent them from taking necessary medications or maintaining adequate hydration

Lancet Diabetes Endocrinol 7:776785

Procedures such as gastric bypass or sleeve gastrectomy have demonstrated significant long-term weight loss and improvement in obesity-related comorbidities, though patients require lifelong monitoring including thyroid function assessment, as malabsorption may affect levothyroxine requirements

The common denominator is the rate and magnitude of weight loss, not the specific medication