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Strains with fluorescently tagged cytoplasmic and cell envelope components used in this study comprise those tagged as follows: cytoplasmic mCherry (DH5( pir ), pTD47), ZipA-mCherry (inner membrane-tagged, TB28, attHKNP5) 44 , LpoB-GFP (MG1655, attHKCB28

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Treatment studies administering folinic acid at doses typically ranging from 0.5 to 2 mg/kg/day reported improvements in communication, irritability, attention, stereotypy, and neurological signs