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It also appears to modulate the gastrointestinal side effects of GLP-1 activation, which may explain why tirzepatide is better tolerated despite being more potent
The removal rate of triglycerides stored in adipocytes decreases with age, but the results of studies regarding changes in the related enzymes and the effects on lifespan are conflicting
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Because SDH is the only enzyme that participates in both the TCA cycle and the ETC, we speculated that the ETC might be compromised in Gclc -deficient FoB, thus explaining the inhibition of SDH and the accumulation of succinate
