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Phentermine at its best produces approximately 5 to 10 percent total body weight loss over a few months

In Phase 3 studies: Participants without diabetes taking orforglipron lost approximately 9% to 10% of body weight over roughly 36 to 40 weeks Participants with type 2 diabetes generally lost around 7% to 8% By comparison, Wegovy's landmark STEP trials reported approximately 14.9% average weight loss over 68 weeks

L-Carnitine: Primarily supports energy production by converting stored fat into fuel, making it a great pre-workout option

As of publication, CMS has not shared how they plan to determine who can and cannot enroll in the program