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The biological rationale for the combination rests on mechanistic complementarity
All efforts were made to minimize animal suffering and to reduce the number of animals used
Semaglutide is specifically formulated for subcutaneous injection, which means it must be placed into the layer of fat just beneath the skin
Start: 200 mcg once daily Increase: Add ~200 mcg every 2 weeks as tolerated Target Range: 400600 mcg once daily Frequency: Once daily Cycle Length: Typically 812 weeks Timing: Any consistent daily time
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