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Among these patients, 45.2% achieved a dose of 1 mg (injectable), and 14.2% reached 14 mg (oral) [1]
Signalling through GLP-1 and GIP receptors involves Gs-coupled pathways, increasing intracellular cAMP, which, downstream, can modulate the expression and/or activity of several fibrosis effectors
Given the regenerative potential of hMSC, understanding how GLP-1-RA affect these cells is crucial for determining further implications of these drugs on tissue homeostasis and metabolic health
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