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Our findings demonstrate that this mucoadhesive, nano-enabled system successfully overcomes the primary bottleneck of conventional therapies (the blood-brain barrier) leading to significantly enhanced neuro-restoration, reduced oxidative stress, and suppressed neuroinflammation in a PD model
J Anal Bioanal Chem
i , HCT116 cells were starved and treated with insulin for indicated times and subjected to cytosolic and membrane fractions, WCLs were collected for IP PDK1 and IB analysis
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