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It must be swallowed whole with plain water and never crushed, split, or chewed
First introduced in Europe in 1966 for parasitic worm infections, its indications later expanded to rheumatoid arthritis and, in the 1990s, as adjuvant therapy for colon cancer
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The physiological relevance of the kinetic uncoupling is that it allows the formation of stable complexes, for example, with ironsulfur clusters or disulfide-bonded interaction partners
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