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Interestingly, some metabolites such as malate, -ketoglutarate, ornithine, glutamate, ornithine, phenylalanine, tryptophan, tyrosine, leucine, and histidine had higher percentage 13 C-labelling in three or more carbon atoms (M+ 3) in the gdh3 / gdh3 mutant compared to wild-type cells grown in 30% U- 13 C 5 proline medium
Since COVID-19 infection in patients with G6PD may independently promote hemolysis, prescribing hydroxychloroquine or chloroquine may exacerbate this hemolytic effect as a result of increased oxidative stress
Studies of the substrate specificity, enzyme-substrate interactions, and the function of lipid
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