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Bullen, H

As an important component of regulating metabolism and immune homeostasis, the vagus nerve can regulate WAT content through the central nervous system to control sympathetic peripheral muscle bundles, and can also regulate the release of GSH and NO to enhance antioxidant capacity and prevent ferroptosis (36)

On top of that, rapid weight loss from GLP-1s can mess with your eustachian tube the small canal that links your middle ear to your throat leading to a feeling of fullness in the ears and contributing to sinus discomfort

Safety was assessed by the number of adverse events and serious adverse events reported during the treatment period