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Treatment Options at Calibrate Calibrate clinicians prescribe only FDA-approved GLP-1 medications, the same ones used in clinical trials and covered by most commercial insurance plans: Weekly injectables: Wegovy, Ozempic, Mounjaro, Trulicity, Zepbound Note: Ozempic, Moujaro, and Trulicity are FDA approved for type 2 diabetes and must be prescribed off-label for weight loss
Without specific proof as to the exact cause of why a GLP-1 could cause a higher risk of developing NAION, we can hypothesize a bit and suggest hypovolemia and dehydration from perhaps weight loss, especially if the patient is getting a medication for hypertension and the weight loss has reduced the need for the hypertensive agent and thus the patient develops hypotension
Most patients report that cold sensitivity diminishes within 26 weeks as their body acclimates to the new metabolic baseline
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