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Menstrual irregularities An analysis of over 410,000 social media posts (self-reported anecdotal evidence) by people taking semaglutide or tirzepatide found that menstrual irregularities were among the most commonly self-reported side effects not well captured in clinical trial data, suggesting this may be more prevalent than official labelling indicates

These are expressed in terms of volume (eg, cups) per pound of body weight

Acknowledgements We are grateful to the staff of the Royal Zoological Society of Antwerp (RZSA) for their support in this study