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Semaglutides weight loss effects have also driven up demand for the drug, leading to high costs, medication shortages and the use of potentially dangerous compounded versions for some

Hoff also noted that HbA1c was better controlled in the semaglutide group with their levels falling by 0.95 while the placebo group saw a decrease of 0.61

For anyone considering it, the safest first step is the same as before the vote: a conversation with a clinician rather than a purchase of unknown origin

However, oral semaglutide (Rybelsus) can increase levothyroxine exposure, so TSH should be monitored when these medications are co-administered, and timing or dosage adjustments may be needed