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Preclinical research summary Preclinical investigations have evaluated AOD9604 in obese murine models and in 3-adrenergic receptor knockout mice, using lipid metabolism and body composition endpoints to support mechanistic hypotheses regarding adipose biology
Standard protocols use 50100 mg/kg via oral gavage or supplemented drinking water, per institutional guidelines
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The trial did not meet its primary efficacy endpoint for weight loss [3]
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