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10.1159/000236023 Pancreatology 39 DildaP
MOTS-c: The cellular energy optimizer MOTS-c (mitochondrial open reading frame of the 12S rRNA type-c) is a mitochondrial-derived peptide produced from DNA inside the mitochondria that helps regulate energy and improve metabolic homeostasis at the cellular level
They are often sufficient for correcting mild dietary deficiencies (e.g., in vegans who dont consume fortified foods) and can sometimes be used for maintaining levels after an initial course of injections, provided absorption is adequately monitored by a healthcare professional
Both forms ultimately provide vitamin B activity, but hydroxocobalamins longer duration in the body means injections can be given less frequently in maintenance therapy
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