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With an extended ~36-hour half-life (versus LHs ~30 minutes), it provides sustained gonadal stimulation [2]
Vigorous agitation generates shear forces and an air-liquid interface that promote peptide aggregation, and it produces foam that traps material away from the solution
Enzyme activity also decreases at lower temperatures
Genetics plays a role here, and people who have genetically lower IgE levels are less likely to have chronic urticaria.[ref] Mast cells, atrial fibrillation, and cardiac diseases: Researchers estimate that there are ~50,000 mast cells/g of human heart tissue
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