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The levels of thiobarbituric acid reactive substances (TBARS) are higher in smokers than in non-smokers with gastric cancer, and smokers have lower levels of SOD, CAT, GPX, GST, GSR and decreased vitamins A, E, and C (64)

Concerns about the potential association between certain diabetes medications and cardiovascular disease meant that in 2010 the FDA approved liraglutide on condition that Novo Nordisk conduct a post-marketing study to evaluate the drug's effect on the incidence of major cardiovascular events (Nielsen, DeChiaro, Goldman)

Is there a published RCT on the specific combination

DPP-4 degrades GLP-1 (7-36) into the non insulinotropic GLP-1 (9-36) (some studies suggest it may have weak insulinotropic activity)