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The mechanistic target of rapamycin (mTOR) is the main negative regulator of autophagy

However, over time, the pancreas may become exhausted and unable to keep up with the demand for insulin, leading to type 2 diabetes.Insulin resistance is also associated with other metabolic abnormalities, including high levels of triglycerides and low levels of HDL cholesterol, a condition known as dyslipidemia

Under the category of diabetes under the Red Cross Eligibility Criteria, the only guideline is that people with diabetes are well controlled and on some sort of insulin or oral medication