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Reduced Inflammation Chronic inflammation is a common factor in various health conditions
In a model of amyotrophic lateral sclerosis (ALS) caused by C9orf72 gene mutations, the pathogenic poly-dipeptide GA50 directly binds to and inhibits SQOR, leading to excessive NLRP3 inflammasome activation in microglia and consequent mitochondrial dysfunction ( A growing body of preclinical work supports this strategy: boosting SQOR activity or reducing H 2 S can protect the nervous system
Many enzymes in our brain and body need vitamin C to do their jobs
Ferroptosis and autoimmune diseases
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