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Incidence of new PDR (R3M0, R3M1) New PDR was detected in 33 of 3068 (1.1%) tirzepatide-exposed individuals and 17 of 3168 (0.5%) tirzepatide-unexposed individuals, a combined incidence rate of 6.9 (95% CI 5.3, 9.0) per 1000 person-years