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The blood glucose was measured before (0 minutes) and after 15, 30, 60, and 120 minutes of glucose/insulin administration, using Truetrack glucometer (Nipro Diagnostics), as also described in our earlier studies (15, 41, 74)
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At the same dose, a 74 kg participant had about 1.4 times the exposure of a 110 kg reference, while a 143 kg participant had about 0.8 times. Weight alone does not set the dose, but it helps explain why the trial mean transfers poorly to bodies outside the studied range
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