The decision hinges on gastric acid exposure and formulation type
Throughout the twentieth century, researchers increasingly recognized its importance in antioxidant defense systems and cellular metabolism
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N Engl J Med 370(15):13831392 Yusuf S, Pfeffer MA, Swedberg K, Granger CB, Held P, McMurray JJ et al (2003) Effects of candesartan in patients with chronic heart failure and preserved left-ventricular ejection fraction: the CHARM-Preserved trial