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Saxenda was the first GLP-1 medication to get approval from the FDA for weight management in adults with obesity and overweight with at least one weight-related health condition as an adjunct to exercise, and lifestyle and dietary modifications
9 This study was the longest in duration of the SURPASS trials thus far, lasting a median of 85 weeks, but study endpoints were assessed in terms of changes from baseline to 52 weeks
Soszyski M et al
A further possibility is that the positive chronotropic effect could be, at least partially, mediated by sympathetic nervous system enhancement, related to the inhibition of the autonomic nervous system [18, 36, 37]
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