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Trim37 maintains PGC fate by inhibiting somatic transition To investigate the fate of PGCs in Trim37 knockout embryos, we first evaluated whether Trim37 deficiency causes apoptosis in PGCs by cleaved caspase-3 staining and terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL) assay
McTigue MA et al
[29] [30] Appetite regulation : They act on centres in the brain that control hunger and fullness, helping to reduce overall caloric intake
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