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2.5.15 Anti-CD3/CD3R 2.5.15.1 Muronomab-CD3 CD3 is a core component of the T cell receptor complex, and oral anti-CD3 antibodies induce tolerogenic effects through T cell anergy, regulatory T cell induction, and anti-inflammatory cytokine production in gut-associated lymphoid tissue, though clinical development was limited by manufacturing discontinuation

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