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Results l-Carnitine attenuated the increased ROS levels in the cytosol and mitochondria of PFOS-treated RTCs and the cell death of such cells We previously demonstrated that N-acetylcysteine (NAC), a ROS scavenger, rescues RTCs from PFOS-mediated apoptosis triggered by autophagy activation because the autophagy inhibition due to 3-methyladenine can block the aforementioned apoptosis 3

Improved hormonal profile with upregulation of tissue 17-HSD (hydroxysteroid dehydrogenase), 3-HSD, follicle-stimulating hormone, luteinizing hormone, and testosterone was observed

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Journal of Trace Elements in Medicine and Biology, 88 , 127603