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Specifically, Asp 21P forms a salt bridge with R242 ECL1 , while Trp 25P forms a hydrogen bond with D244 ECL1 and pi-pi stacking with W249 ECL1 , which was stabilized by Phe 22P
We refer the reader to Pin et al
But the body composition changes, the shift from losing general weight to specifically losing fat while preserving lean tissue, become more apparent over months of consistent use
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