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Both medications represent breakthrough advancements in weight management, far exceeding what was possible even five years ago
Ann N Y Acad Sci 512:237247

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Intermuscular adipose tissue-derived inflammatory adipokines, exacerbated by aging, obesity, and sedentary behavior, promote both fat accumulation and chronic inflammation within skeletal muscle, driving adipogenic differentiation at the expense of myogenesis and thereby contributing to reduced muscle quality and increased metabolic risk [81]
